Our research is focused on three related topics: the control of hunger, thirst, and body temperature. A general principle emerging from our recent work has been the discovery that homeostatic circuits – long thought to function primarily by reacting to physiologic imbalances – instead utilize sensory cues to anticipate those physiologic changes and then adjust behavior preemptively. An ongoing interest of the lab is to understand how homeostatic circuits integrate sensory information from the outside world with internal signals arising from the body in order to generate and shape goal-directed behaviors.
For more information, go to: www.knightlab.ucsf.edu
Zachary Knight earned his B.A. in Chemistry from Princeton University and his Ph.D. in Chemical Biology from UCSF. Following postdoctoral training at Rockefeller University, Dr. Knight joined the Department of Physiology as an Assistant Professor.
Dr. Knight is a Robertson Neuroscience Investigator of the New York Stem Cell Foundation. His work has been recognized by awards from the Sloan, McKnight, Rita Allen, Klingenstein, and Brain and Behavior Research Foundations, as well as NIH New Innovator and Pathway to Independence Awards. Most recently, Dr. Knight received a Pathway Award from the American Diabetes Association and the Helmholtz Young Investigator in Diabetes Award.
Lisa Beutler, Postdoctoral
Ling Bai, Postdoctoral
Jacob Carlson, Postdoctoral
Oliver Miller, Postdcotoral
Seonghyun (Jamie) Ahn, Specialist
Seher Kosar, Specialist
Rachel Essner, Specialist
Chris Zimmerman, Neuroscience Graduate Student
Yiming Chen, Neuroscience Graduate Student
Tzu-Wei Kuo, Neuroscience Graduate Student
David Leib, Neuroscience Graduate Student
Laura Wise, Adminstrative Assistant