Anatol Kreitzer, Ph.D.

Associate Professor, UCSF School of Medicine

PhD in Neurobiology, Harvard University
BA in Linguistics, University of California - Berkeley

The research in the Kreitzer laboratory is focused on understanding the mechanisms controlling cellular, synaptic, and circuit function in the basal ganglia that control motor planning, learning, and movement. The long-term goal is to understand how neural activity and plasticity in these circuits shapes motor behavior and how neurological disorders such as Parkinson's disease (PD) and Huntington's disease (HD) affect synaptic, cellular, and circuit function in the basal ganglia.


The Kreitzer lab seeks to answer:

  1. What is the functional role of neural activity in direct and indirect pathway MSNs?
  2. How is neural activity in the direct and indirect pathways integrated in basal ganglia output nuclei?
  3. How do striatal microcircuits function to shape direct and indirect pathway output?
  4. What role does dopamine play in striatal microcircuit function?
  5. How does loss of dopamine impact basal ganglia circuit function?
  6. How does dopamine modulate synaptic plasticity in the striatum?
  7. How can we restore basal ganglia circuit function in the absence of dopamine, such as during PD?

Anatol Kreitzer earned his B.A. in Linguistics from University of California - Berkeley and his Ph.D. in Neurobiology from Harvard University. Following postdoctoral training at Harvard and Stanford, Dr. Kreitzer joined the Department of Physiology as an Assistant Professor. Dr. Kreitzer is also an Associate Investigator with the Gladstone Institute of Neurological Disease.

Chris Donahue, Postdoctoral Fellow

Lisa Gunaydin, Postdoctoral Fellow

Arnaud Lalive, Postdoctoral Fellow

Tony Lien, Postdoctoral Fellow

Max Liu, Graduate Student

Scott Owen, Postdoctoral Fellow

Tom Roseberry, Graduate Student

Delanie Schulte, Research Associate